Despite its name, acne rosacea is not a disease of the pilosebaceous follicles as juvenile acne but originally vascular disease.
 This common condition - 2 to 3% - of the population mainly affects women in perimenopause.
 Recently (09/1999), Helicobacter pylori has been suspected in the pathogenesis of rosacea (to).
 
 SYMPTOMATOLOGY
 Rosacea evolves over several years by outbreaks aggravated by changes in temperature, alcohol, spices, sun exposure, the emotions.
 
 There are 4 phases
 Stadium flush ie episodes of erythema occurring suddenly in cironstances triggers as stress, food, sun, etc ….
 This erythema reached the cheeks and nose with conjunctively sometimes hyperemia.
 Stage ie the blotches of erythema  and + / - swelling of the cheeks and forehead
 Stage appearance with inflammatory episodes of inflammatory papules and pustules but without reaching the follicle and sebaceous cyst therefore no and comedones
 The mostly male rhinophyma: facies rubicond large nose and red, bumpy with Sebaceous hyperplasia and reshuffle of fibrous connective tissue 

 The complications are mostly eye: conjunctivitis, blepharitis (inflammation of the eyelids board) and more rarely keratitis. 
 
 DIFFERENTIAL DIAGNOSIS
 —- Acne
 —- Seborrheic Eczema
 —- Contact dermatitis or iatrogenic (steroid)
 —- Lupus.
 
 TREATMENT
 It is imperative to remove the elements, circumstances, food, etc … which aggravate rosacea: stress, alcohol, sun, rapid changes in temperature, etc …
 Local corticosteroid is against inappropriate despite its spectacular performance that leads to abuse and increased long-term (with corticodépendance)
 
 Tetracyclines account for the treatment of advanced pustules.
 As in the juvenile acne, treatment is extended over several months or even one or two years and is generally well tolerated.
 
 THE METRODINAZOLE is an alternative (FLAGYL 500 mg / d 15 days and 125 mg / J one or two months) with relay by the local form cream 1%
 
 CATAPRESSAN (1 / 2 cp / day) should be evaluated in the initial stages
 
 Roaccutane is the treatment of rhinophyma beginner. In advanced forms, surgery may be proposed.
 
 Physical methods (electro-laser, cryotherapy) are effective but requires the provisional result of the practice fairly regularly.
 
 To learn more www.rosaceainfo.com/
 
 The best current treatment seems to be metronidazole (Flagyl) Topical preparations basis masterful at 1% or the ROZEX GEL pursuant morning and evening TETRALYSAL + 150 MG + 2gelules the evening a special regime.
 
 ADDITIONAL INFORMATION
 Dr. Ludovic ROUSSEAU - Dermatologist
 Dermatonet.com webmaster, site of Dermatology
 The blotches and rosacea are more common among people with a clear phototype (skin and eyes)
 The treatment of rosacea laser vascular often provides interesting results
 We should not hesitate to apply the cream base has steadily metronidazole because rosacea relapses are frequent
 Other information about the blotches and rosacea in dermatonet
 
 
 Cyclin-small doses to treat rosacea: it works!
 Sanchez J et al. "A randomized double-blind, placebo-controlled trial of the combined effect of doxycycline hyclate 20 mg tablets and metronidazole 0.75% topical lotion in the treatment of rosacea." J Am Acad Dermatol 2005; 53: 791-7. © Copyright 2005 http://www.jim.fr
 Creation Date: 02 December 2005
 
 The treatment of rosacea is based primarily on cyclins that are both effective on pustular rash papulopustular skin but also eye damage.
 
 A randomized double-blind placebo was carried out to assess the interests of low-dose doxycycline as the dosage used in this study was 40mg/jour while the usual dose is 100 mg / day. Two groups of patients were compared: one in doxycycline was administered for 12 weeks in combination with topical metronidazole and then for 4 weeks alone. In the other group (placebo), metronidazole was applied for 12 weeks, combined with taking pills to placebo.
 
 The severity of Rosaceae was not negligible because of the severity score (maximum 20), was on average 9.5. It was noted in the treated group a reduction, significant from the 4th week of treatment of inflammatory lesions is now the 16th week. The severity scores were also significantly reduced in the treated group compared to placebo.
 
 The treatment of rosacea by the cyclin is not a novelty in itself but instead the effectiveness of low doses of doxycycline is less well known. These small doses of antibiotics act through an anti-inflammatory activity and the reduction in dosage could reduce the risk of disruption of the bacterial flora, oral, vaginal or digestive. Moreover, this study shows that the combination of topical antibiotics metronidazole is much more effective than topical metronidazole alone.